Although our results suggest that there has been progress in reducing stigmatizing attitudes to mental health disorders such as depression, what is more important for us as educators, is that we do not seem to be changing the attitudes of students, who persist in holding stigmatizing attitudes. Levels of regard toward patients with mental health conditions remain similar in final-year medical students, as compared with those in first years of the course. Furthermore, there are differences in attitudes between different groups, for example, less tolerance of psychotic symptoms by South Asian students, or higher regard for those with depression in students who have personal experience of mental health disorders. However, negative attitudes to medically unexplained symptoms remain highest and appear to deteriorate over the course of medical studies, and this matter needs to be urgently addressed. Chronic conditions that are not easily remedied may attract more stigmatizing attitudes, reflecting frustration, and perhaps an expectation that Medicine should yield more immediate and satisfying patient recovery.