Specifically, during my policy fellowship, I was tasked to help reconcile the scientific research community’s pursuit of research that, while therapeutic in intent, may be used nefariously, with the government’s oversight of such research to guard against possible misuse. This was in the context of whether to allow two manuscripts revealing how H5N1, the deadly bird-flu virus, could be made more lethal while simultaneously identifying mutations that could be used to create vaccines. Although the manuscripts were ultimately published, the process by which that decision was made was a deliberate one, resulting in taking a painstaking look at how research is conducted. The process involved discussion with scientists, policymakers, and bureaucrats to address all possible concerns. Ultimately, new policies were created that will clarify the type of research being conducted and how to communicate findings responsibly.