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Acad Psychiatry 31:388-401, October 2007
doi: 10.1176/appi.ap.31.5.388
© 2007 Academic Psychiatry
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Special Article

Psychosomatic Medicine: The Scientific Foundation of the Biopsychosocial Model

Dennis H. Novack, M.D., Oliver Cameron, M.D., Ph.D., Elissa Epel, Ph.D., Robert Ader, Ph.D., Shari R. Waldstein, Ph.D., Susan Levenstein, M.D., Michael H. Antoni, Ph.D. and Alicia Rojas Wainer, M.D.

Received December 4, 2005; revised November 15, 2006; accepted November 20, 2006. From Drexel University College of Medicine, Office of Educational Affairs, Philadelphia, Pennsylvania. Address correspondence to Dr. Novack, Drexel University College of Medicine, Office of Educational Affairs, 2900 Queen Lane, Philadelphia, PA 19072; dennis.novack{at}drexelmed.edu (e-mail).

OBJECTIVE: This article presents major concepts and research findings from the field of psychosomatic medicine that the authors believe should be taught to all medical students. METHOD: The authors asked senior scholars involved in psychosomatic medicine to summarize key findings in their respective fields. RESULTS: The authors provide an overview of the field and summarize core research in basic psychophysiological mechanisms—central nervous system/autonomic nervous system, psychoneuroimmunology, and psychoendocrinology—in three major disease states—cardiovascular, gastrointestinal, and HIV virus infections. CONCLUSIONS: Understanding the core scientific concepts and research findings of psychosomatic medicine should provide medical trainees with a scientific foundation for practicing medicine within a biopsychosocial model of care.







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